Resources: Sickle Cell Trait

Featured in the lessons:

• Newborn Screening Specimen Collection Video
• March of Dimes' Sickle Cell Fact Sheet

Course references:

• Sickle Cell Information Center
• Newborn Screening Case Management
• About Sickle Cell Disease
• About Sickle Cell Disease in teens
• Sickle Cell Anemia: Signs and Symptoms — MayoClinic.com
• The American Sickle Cell Anemia Association
• March of Dimes
• Centers for Disease Control and Prevention
• Newborn Screening Fact Sheets
• Newborn Screening Follow Up Guidelines

Other references:

• Aidoo, M., Terlouw, D. J, Kolczak, M.S., McElroy, P.D., ter Kuile, F., Kariuki S., Nahlen, B.L., Lal, A.A., & Udhayakumar, V. (2002). Protective effects of the sickle cell gene against malaria morbidity and mortality. The Lancet, 359:9314, 1311-1312
• Adams, R.J., et al. (1997). Long-term stroke risk in children with sickle cell disease screened with transcranial doppler. Annals of Neurology, 42, 699-704.
• Adams, R.J., et al. (1998). Prevention of first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasound. The New England Journal of Medicine, 339, 5-11.
• Ashley-Koch, Yang & Olney. (2000). Sickle Hemoglobin (Hb S) and Sickle Cell Disease: A HuGE Review. American Journal of Epidemiology, 151:9, 839-845.
• Boyd, J.H., Macklin, E.A., Strunk, R.C., & DeBaun, M.R. (2006). Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood, 108 (9), 2923-2927.
• Carlson, K.J., Eisenstat, S.A., & Ziporyn, T.D. (2004). The New Harvard Guide to Women's Health (502). Cambridge, MA: Harvard University Press.
• Centers for Disease Control and Prevention. (2007). Sickle Cell Disease and Other Hemoglobinopathies. Newborn Screening Quality Assurance Program.
• The Council of Regional Networks for Genetics Services (CORN). (1995). National Newborn Screening Report—1992. New York, NY: The Council of Regional Networks for Genetic Services;1995.
• Eckman, J. & Platt., A. (2004). Sickle Cell Information Center Protocols.
• Forget B.G., Higgs, D.R., Steinberg, M. & Nagel, R.L. (2001) Disorders of Hemoglobin: Genetics, Pathophysiology and Clinical Management. Cambridge University Press; Cambridge, UK
• Information Center for Sickle Cell and Thalassemic Disorders. (2002). Transient Aplastic Crisis in Hemolytic Anemias
• Kark, J. (2000). Sickle Cell Trait.
• Kaye, C. & Committee on Genetics. (2006). Newborn Screening Fact Sheets. Pediatrics, 118, 934-963.
• Lab Tests Online. (2009). Hemoglobin Variants.
• Lane, P.A., Buchanan, G.R., Hutter, J.J., Austin, R.F., Britton, H.A., Rogers, Z.R., & Lloyd-Puryear, M.A, for the Sickle Cell Disease Care Consortium. (2001). Sickle Cell Disease in Children and Adolescents: Diagnosis Guidelines for Comprehensive Care, and Care Paths and Protocols for Management of Acute and Chronic Complications.
• Lin, K. & Barton, M. (2007). Screening for Hemoglobinopathies in Newborns: Reaffirmation Update for the U.S. Preventive Services Task Force. Evidence Synthesis No. 52. Rockville, MD: Agency for Healthcare Research and Quality. AHRQ Publication No. 07-05104-EF-1.
• National Collegiate Athletics Association. (2009). Testing recommended for sickle cell trait status.
• National Diabetes Clearing House. (2008). Sickle Cell Trait and Other Hemoglobinopathies and Diabetes: Important Information for Physicians.
• National Heart Lung and Blood Institute.
• Pegelow, C.H., Macklin, E.A., Moser, F.G., Wang, W.C., Bello, J.A., Miller, S.T., Vichinsky, E.P., DeBaun, M.R., Guarini, L., Zimmerman, R.A., Younkin, D.P., Gallagher, D.M., & Kinney, T.R. (2002). Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Blood, 99(8), 3014-18.
• Quinn, C.T., Rogers, Z.R., & Buchanan, G.R. (2004). Survival of Children with Sickle Cell Disease. Blood, 103/11, 4023-4027.
• Section on Hematology/Oncology and Committee on Genetics. (2002). Health Supervision for Children with Sickle Cell Disease. Pediatrics 109, 526-535.
• Smith, W.R., et al. (2008). Daily assessment of pain in adults with sickle cell disease. Annals of Internal Medicine, 148, 94-101.
• Southwestern Comprehensive Sickle Cell Center. (2007).
• Texas Department of State Health Services. (2007). Newborn Screening Case Management Program.